Aptima® Trichomonas Vaginalis Test (ATV)

The most common curable STI

Despite being the most common curable STI, Trichomonas vaginalis (TV) is more prevalent than chlamydia (CT) and gonorrhea (NG) combined.1 3.7 Million TV cases occur annually in the U.S. Many different conditions may cause symptoms similar to TV, and co-infections can be common, making accurate diagnosis imperative for effective TV treatment.2,3

Up to 50% of trichomoniasis infections are missed by wet mount4

Wet mount testing sensitivity declines over time as specimens are often inadequate or lack viable, motile organisms.5


Motile organisms decrease rapidly6

Nucleic acid amplification testing (NAAT) is recommended for the diagnosis of trichomoniasis.7


The use of highly sensitive and specific tests, such as NAAT, are recommended over less-sensitive methods including wet-mount microscopy.8


Accurate TV detection, with or without symptoms

Our Aptima Trichomonas vaginalis assay is an FDA-cleared nucleic acid amplified test (NAAT) for trichomoniasis detection. Along with detecting trichomoniasis in both symptomatic and asymptomatic cases, it requires only a fraction of one organism to detect up to 100% of TV infections.9

Performance data by sample type9
Specimen TypeSensitivity (95% Cl)Specificity (95% Cl)
Aptima® Multitest Swab
(Vaginal Sample)
100% (94.7–100)98.2% (96.7–99.0)
Aptima® Unisex Swab
(Endocervical Sample)
100% (94.6–100)98.1% (96.7–98.9)
ThinPrep® Solution100% (95.6–100)98.6% (97.4–99.2)

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1. CDC. Incidence, Prevalence and Cost of Sexually Transmitted Infections in the United States. Published February 2013. Accessed August 20, 2020. http://www.cdc.gov/std/stats/sti-estimates-fact-sheet-feb-2013.pdf. 2. Kent HL. Epidemiology of vaginitis. Am J Obstet Gynecol. 1991;165(4 Pt 2):1168-1176. 3. Thomason JL and Gelbart SM. Trichomonas vaginalis. Obst Gynecol. 1989;74(3)2:536-541 4. Nye MB, et al. Comparison of APTIMA Trichomonas vaginalis transcription-mediated amplification to wet mount microscopy, culture, and polymerase chain reaction for diagnosis of trichomoniasis in men and women. Am J Obstet Gynecol. 2009;200(2):188.e1-7. doi: 10.1016/j.ajog.2008.10.005. 5. Garber G, et al. The laboratory diagnosis of Trichomonas Vaginalis. Can J Infect Dis Med Microbiol. 2005; 6(1):35-38. 6. Kingston MA, et al. ‘Shelf life’ of Trichomonas vaginalis. Intl J STD AIDS. 2003; 14(1):28-29. 7. ACOG. Vaginitis in Nonpregnant Patients. ACOG Practice Bulletin. Number 215. Obstet Gynecol. 2020;135(1):e1-e17. 8. CDC. Sexually Transmitted Diseases Treatment Guidelines, 2015. MMWR. 2015;64(3). 9. Aptima Trichomonas vaginalis Assay [package insert]. 503684 Rev. 001. San Diego, CA: Hologic, Inc.; 2016