Comprehensive Solutions for
STI Testing

STIs Impact the Health of Communities Across the USA

1 in 5

1 in 5
people have an STI on a any given day1

Many STIs present with similar symptoms but require different treatments.2 When left untreated, the long term implications can be serious:3

Upper Genital Tract Infections
Infertility
Chronic Pelvic Pain
Cervical Cancer
Chronic Infection

Estimated Prevalence of STIs in the United States1

USA HSV-2
USA Trichomoniasis
USA Chlamydia
USA Gonorrhea
Don't Let Asymptomatic Become Problematic

Don’t Let Asymptomatic Become Problematic

Symptoms don’t necessarily correlate with patient harm, so screening for certain STIs is crucial.3

The CDC recommends NAAT as the preferred method for accurate chlamydia (CT) and gonorrhea (NG) screening of patients.2

  • Asymptomatic STIs increase the potential for sustained transmission in the community.3
  • Screening efforts for CT and NG focus on women between the age of 15–24 who identify as being sexually active.2,4-7

Market-Leading NAAT Solutions

Our broad array of highly sensitive NAATs accurately detect pathogens that cause STIs including chlamydia, gonorrhea, trichomoniasis, Mycoplasma genitalium and herpes simplex virus.

Aptima Combo 2® CT/NG Assay

Aptima Combo 2® CT/NG Assay

Simultaneous detection of Chlamydia trachomatis and Neisseria gonorrhoeae with high clinical sensitivity in asymptomatic and symptomatic patients.8

Aptima® Trichomonas vaginalis Assay

Aptima® Trichomonas vaginalis Assay

NAAT that offers superior sensitivity over wet mount or DNA probe method for detecting Trichomonas in women.9,10

Aptima® Mycoplasma genitalium Assay

Aptima® Mycoplasma genitalium Assay

FDA-cleared NAAT with up to 100% sensitivity to accurately identify M. gen11

Aptima® HSV 1 & 2 Assay

Aptima® HSV 1 & 2 Assay

Differentiates between HSV-1 and HSV-2 with high accuracy to support targeted counseling and management.12

Let’s Connect

Have a question or need to talk to a Hologic team member? We’re here to help.

1. Kreisel KM, Spicknall IH, Gargano JW, Lewis FMT, Lewis RM, Markowitz LE, Roberts H, Johnson AS, Song R, St Cyr SB, Weston EJ, Torrone EA, Weinstock HS. Sexually Transmitted Infections Among US Women and Men: Prevalence and Incidence Estimates, 2018. Sex Transm Dis. 2021 Apr 1;48(4):208-214. doi: 10.1097/OLQ.0000000000001355

2. CDC. Morbidity and Mortality Weekly Report Sexually Transmitted Infections Treatment Guidelines, 2021 Centers for Disease Control and Prevention MMWR Editorial and Production Staff (Serials) MMWR Editorial Board.; 2021. Accessed November 24, 2025. https://www.cdc.gov/std/treatment-guidelines/STI-Guidelines-2021.pdf

3. Ghanem K. & Tuddenham S. Screening for sexually transmitted infections. UpToDate. Last updated April 21, 2020. Accessed November 7, 2025. https://www.uptodate.com/contents/screening-for-sexually-transmitted-infections.

4. Opt-Out Screening -. Chlamydiacoalition.org. Published 2021. Accessed November 24, 2025. https://chlamydiacoalition.org/opt-out-screening/

5. Chlamydia, Gonorrhea, and Syphilis. www.acog.org. Published April 2024. Accessed November 24, 2025. https://www.acog.org/womens-health/faqs/chlamydia-gonorrhea-and-syphilis

6. US Preventive Services Task Force. Screening for Chlamydia and Gonorrhea: US Preventive Services Task Force Recommendation Statement. JAMA. 2021;326(10):949–956. doi:10.1001/jama.2021.14081

7. Screening for Nonviral Sexually Transmitted Infections in Adolescents and Young Adults. PEDIATRICS. 2014;134(1):e302-e311. doi:https://doi.org/10.1542/peds.2014-1024

8. Aptima Combo 2 Assay. US package insert AW-25929-001, Hologic, Inc..; 2023.

9. Aptima Trichomonas vaginalis Assay. US package insert AW-27552-001. Hologic, Inc..; 2024.

10. Nye MB, Schwebke JR, Body BA. Comparison of APTIMA Trichomonas vaginalis transcription-mediated amplification to wet mount microscopy, culture, and polymerase chain reaction for diagnosis of trichomoniasis in men and women. Am J Obstet Gynecol 2009;200:188.e1-188.e7.

11. Aptima Mycoplasma genitalium assay. US package insert AW-17946. Hologic, Inc..; 2024.

12. Aptima HSV 1 & 2 assay. US package insert AW-15346-001. Hologic, Inc.; 2021.